The 5 Stages of Biofilm Development
Greetings. New Zealand naturopath, Eric Bakker,
author of Candida Crusher. Thanks for checking out my video today. I’m going to talk about
the different stages of biofilm development. There are basically five stages of how biofilms
develop in your body. We’re going to go through those stages and just sort of explain a little
bit about them. The five different stages are attachment,
adhesion, aggregation, growth and maturation, and detachment. Because when they detach,
then you’re going to go and get attachment somewhere else. This is how colonies break
off. When the high-rise building gets big enough, a couple of stories break off, they
move somewhere else, and they form another building complex somewhere else. That’s what
happens with biofilm. Stage one is attachment. Basically, bacteria
come into the body when there’s a vulnerability or a weakness, particularly when the body
is susceptible with low levels of cortisol or high levels of cortisol. When there are
very low levels of beneficial bacteria. When a person has been taking lots of antibiotics
or drinking lots of alcohol or has a high stress life. So the conditions have to be
right for the attachment to occur. Attachment can occur anywhere, on the teeth, in the nose,
in the throat, tonsils, urinary tract, bladder, many different areas in the digestive system
where an attachment can occur. The conditions need to be right. The bacteria will settle
in nicely there and bind and attach to a surface area.
Stage number two, the adhesion. So now, the bacteria have to adhere more firmly into the
wall, for example, the intestinal wall. They anchor in there. Anchoring means, they form
a nice sort of strong, firm platform on how they can build other bacteria. And again,
susceptibility has to really be there. Conditions have to be right. I typically find a lot of
biofilm occurring in people with very low levels of lactobacillus when we do the stool
test, the CDSA stool test, which I commonly do with patients. If we get very low levels
of beneficials like one or even NG, like no growth, we can almost guarantee that the patient’s
going to have a lot of biofilm development. If the police are gone, before you know it,
the criminals hang around town. If the police are completely gone and even the good citizens
go away like the E.coli, we can even get ISIS or like seriously bad gangsters and mobsters
hanging around, really bad bacteria. We can get like Citrobacter, for example, which I
commonly see in three or four plus in very sick people. Adhesion needs to take place.
That’s the second stage. The third stage is aggregation, so this is
the formation of the micro colonies. So now, we’ve got one or two floors of the high-rise
apartment. Before you know it, there are three or four, five stories going up. And I can
remember when the Twin Towers was destroyed in that horrific incident in New York years
ago, how long it took for the new towers to be developed. They’re beautiful now, the new
towers. And it’s wonderful watching all the photos of how the high rise just kept going
up and up. And then there would be a problem maybe with material supply, but then they
got another 10 stories and 20 stories. Now, we’ve got this beautiful big building again.
Same with these micro colonies, but in this case, the floors got up quite rapidly. Because
these colonies can aggregate very quickly. And before you know it, one building turns
to two buildings and we’ve got hundreds of high-rises all in this congregation. That’s
aggregation. So the fourth stage is the growth and maturation.
Now, these bacteria aggregates form very complex structures where the cells start nourishing
each other and feeding each other. The exopolysaccharide-enclosed micro colonies are separated from each other,
but there are channels running between them where nutrients and water can run to feed.
So it’s a bit like sewage systems, electrical systems in buildings, which is going to really
allow the people to enjoy living in those buildings and to keep coming back and build
bigger colonies. Food supply increases. Air increases. All these things are conducive
toward very good and powerful biofilm formation. And that’s what occurs. Nutrient and oxygen
availability are very important, and they occur beautifully in these biofilms during
the growth and maturation stage. And the fifth stage, of course, is the detachment
stage when a couple of the stories on the top of the building will sort of float downstream
and then they’ll be looking for another site where they can attach themselves, and then
the whole thing starts all over again. And before you know it, large parts of the digestive
tract can be full of biofilm or in the nose. You can have a staph infection in the nose.
It can be resistant to antibiotics, for example. I found it interesting that ozone therapy
works quite well in the nose for eradicating the staph resistant MRSA. The bacteria that
is resistant to antibiotics. Ozone seems to be a good one for blood, but also inhaling.
There are ways of eradicating it, but we’ll talk about that in another video. When a single
bacterium is dispersed or aggregates of bacterium are dispersed and they move away, they will
attach. They detach and they attach, and then they form a whole new biofilm.
I hope that gives you a bit of an insight into the five stages of biofilm development.
Most patients I see with chronic gut problems have got biofilm. Biofilm wasn’t taken really
seriously by the scientific community until recently. But if we go back many years ago,
people never even believed that biofilm existed. But now we realize it’s one of the biggest
problems facing the health care profession, is biofilm identification and, particularly,
eradication of biofilm. So let’s talk about that in some other videos.
Thanks for tuning in.